OxThera AB, a privately-held biopharmaceutical company dedicated to improving the lives of people with Primary Hyperoxaluria (PH), announces the publication of an article in Pediatric Nephrology, on the significant correlation between plasma oxalate and kidney function in …

Today there is no curative treatment available. Oxthera’s lead asset Oxabact consists of an orally delivered composition of live bacteria, Oxalobacter formigenes. Primary hyperoxaluria is a rare autosomal recessive disorder leading to markedly elevated levels of endogenous oxalate i plasma and urine. High levels of oxalate cause kidney damage, including crystallization of oxalate in tissues and in the kidney. OxThera AB is a Swedish biotech company developing a new treatment for primary hyperoxaluria (PH) - a rare genetic and devastating disease with fatal outcomes. Currently pharmaceutical treatment is Oxthera develops a novel treatment for patients with the ultra-orphan kidney disease primary hyperoxaluria.

Elimination occurs primarily via the kidneys. Primary hyperoxaluria is a rare autosomal recessive disorder leading to markedly elevated levels of endogenous oxalate i plasma and urine. High levels of oxalate cause kidney damage, including crystallization of oxalate in tissues and in the kidney. OxThera AB, a privately-held biopharmaceutical company dedicated to improving the lives of people with Primary Hyperoxaluria (PH), announces the publication of an article in Pediatric Nephrology, on the significant correlation between plasma oxalate and kidney function in … OxThera currently has two products in its pipeline: Oxabact® for the treatment of Primary hyperoxaluria, and Oxazyme ® , an oxalate decarboxylase, for the treatment of oxalate superabsorption and kidney failure in enteric hyperoxaluria. Oxthera develops a novel treatment for patients with the ultra-orphan kidney disease primary hyperoxaluria. In patients, mostly children, this life-threatening disease accumulates oxalate in the body and the oxalate forms insoluble crystals and stones in different organs (kidney, liver, heart and eyes). OxThera AB, a Stockholm-based privately-held biopharmaceutical company, today announced that it has initiated a clinical study in in Primary Hyperoxaluria.

The aim of this trial was to investigate whether treatment involving an oxalate-metabolising bacterium (Oxalobacter OxThera AB, a Stockholm -based privately-held bio pharmaceutical company, today announced that the Phase 3 study with Oxabact ® in Primary Hyperoxaluria 2021-02-02 Primary Purpose: Treatment: Official Title: A Phase III Double-blind, Randomised Study to Evaluate the Long-term Efficacy and Safety of Oxabact in Patients With Primary Hyperoxaluria: Actual Study Start Date : January 9, 2018: Estimated Primary Completion Date : April 2021: Estimated Study Completion Date : … OxThera AB, a Stockholm-based privately-held biopharmaceutical companyand leader in the field of microbiome derived biotherapeutics, today announced a poster presentation showing encouraging Oxabact ® efficacy and safety data from the long-term study OC5-OL-01, at the Annual Meeting of the American Society of Nephrology Kidney Week 2018 in San Diego. STOCKHOLM, Sweden--(BUSINESS WIRE)--OxThera today announced that all 42 patients have been enrolled in their pivotal phase II/III study using Oxabact ™ for the treatment of Primary Hyperoxaluria. Primary Outcome Measures : .

OxThera AB, a privately-held biopharmaceutical company dedicated to improving the lives of people with Primary Hyperoxaluria (PH), announces the publication of an article in Pediatric Nephrology, on the significant correlation between plasma oxalate and kidney function in …

Uppdatering: Di skrev i Hitta information om Oxthera AB (publ). Adress: Sturegatan 56, Postnummer: 114 36. Telefon: 08-660 02 .. Oxabact planeras nu att användas för behandling av den sällsynta sjukdomen korttarmssyndrom (Short Bowel Syndrome, SBS).

2021-02-02

Dedicated to improving the care and treatment of, and finding a cure for Oxalosis, Primary Working with Oxthera and SymbioPharm to inspire hope through medical advances. Primary Hyperoxaluria (PH) is a rare autosomal recessive inborn error of to OxThera AB, Sweden, for Oxalobacter formigenes strain HC-1 for the treatment of primary hyperoxaluria.

The… Read More Matthew Gantz Appointed CEO of Oxthera 2017-07-05 Primary hyperoxaluria is a rare autosomal recessive inherited disorder of glyoxylate metabolism that causes an endogenous overproduction of oxalate. Oxalate cannot be degraded in humans and is mostly eliminated by the kidneys. The oxalate overproduction leads to kidney stones, nephrocalcinosis and kidney damage. Patients with primary hyperoxaluria experience kidney stones from a young age and can develop progressive oxalate nephropathy. Progression to kidney failure often develops over a number of years, and is associated with systemic oxalosis, intensive dialysis, and often combined kidney and liver transp … Primary Hyperoxaluria is a rare autosomal recessive disorder leading to markedly elevated levels of endogenous oxalate in plasma and urine. High levels of oxalate cause kidney damage, including crystallization of oxalate in tissues and in the kidney.
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Primary hyperoxaluria. Oxabact. Live bacteria.

OxThera AB, a privately-held biopharmaceutical company dedicated to improving the lives of people with Primary Hyperoxaluria (PH), today announced that, based on a positive opinion from the Paediatric Committee (PDCO), the EMA has agreed to the proposed PIP for Oxalobacter formigenes in the treatment of primary hyperoxaluria. OxThera announces completion of recruitment in Phase 3 ePHex study with Oxabact® in patients with primary hyperoxaluria Mon, Apr 06, 2020 07:40 CET OxThera AB, a privately-held biopharmaceutical company dedicated to improving the lives of people with Primary Hyperoxaluria (PH), announced today that it has completed enrollment in its Oxabact ePHex phase III study. ePHex - An OxThera Clinical Trial in Primary Hyperoxaluria March 26, 2019 · Qualified patients willing to participate will undergo a 52 week study.
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OxThera AB, a privately-held biopharmaceutical company dedicated to improving the lives of people with Primary Hyperoxaluri OxThera receives positive decision from EMA on Paediatric Investigational Plan (PIP) for treatment of primary hyperoxaluria with Oxalobacter formigenes | Placera

18 Jul 2019 The Primary Hyperoxaluria (Genito Urinary System And Sex Hormones) Dicerna Pharmaceuticals Inc; Intellia Therapeutics Inc; OxThera AB OxThera. Collaborator: FP7-SME-2013 Research for the benefit of SMEs program Primary Hyperoxaluria, Biological: Oxalobacter formigenes, Phase 2 PDF | On Jul 1, 2008, Christiaan van Woerden published Primary hyperoxaluria type 1 : clinical, genetic and biochemical studies | Find, read and cite all the OxThera AB is a Swedish biotech company developing a new treatment for primary hyperoxaluria (PH) - a rare genetic and de… See more. Headquarters. 2 Nov 2008 Primary hyperoxaluria type 1 (PH1) is a rare metabolic disorder OxThera.

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OxThera AB, a Stockholm -based privately-held biopharmaceutical company, today announced that it has initiated a clinical study in in Primary Hyperoxaluria.

Primary hyperoxaluria is a rare genetic disorder that affects primarily children causing progressive kidney damage, calcification of the kidneys, and finally kidney failure. Today there is no curative treatment available. Oxthera’s lead asset Oxabact consists of an orally delivered composition of live bacteria, Oxalobacter formigenes. Primary hyperoxaluria is a rare autosomal recessive disorder leading to markedly elevated levels of endogenous oxalate i plasma and urine. High levels of oxalate cause kidney damage, including crystallization of oxalate in tissues and in the kidney. OxThera AB is a Swedish biotech company developing a new treatment for primary hyperoxaluria (PH) - a rare genetic and devastating disease with fatal outcomes. Currently pharmaceutical treatment is Oxthera develops a novel treatment for patients with the ultra-orphan kidney disease primary hyperoxaluria.